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Good for Sherlock and John too, now that I consider it ...
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Press on!
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Wow, I really like the idea of human pressing machine from "The Engineers Thumb" making an appearance in Sherlock! It was one of my guesses in the "dark twists" thread because I thought at the time that a stuff like this will be irresistible for horror-lover like Mark Gatiss - and that he will definitely bring it into the story eventually. Now it looks very promising - cool!
As to where we could find human pressing machines in London... well, I guess it will be something similar like the thing in the canon - the ordinary looking room without furniture which will be later revealed to be a hydraulic press in disguise.
And yes, John and Sherlock could definitely be pressed by it until they are forced to be glued to each other from head to toe, I subscribe to that!
I just hope none of our heroes will loose a thumb or some other limb in this adventure - I like them whole and fit, thank you!