I've seen Sherlock Holmes: A Working Hypothesis  and would recommend it if anybody's in the area.  It's a fantastic setting, the audience participation was fun and it was interesting to see a different interpretation of the characters. 

Here's a review, but it is quite spoilery, including photos.  It doesn't give everything away, so it's safe to look if you want to have more of an idea what it's about beforehand, but if you prefer it to be completely spoiler-free, then stay away!