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February 27, 2014 10:27 pm  #21


Re: An interesting NEW perspective

Swanpride wrote:

I say it one last time (because we are going in circles here): Mary is a trained assassin who is standing directly in front of Sherlock. She has the pick to shot him either in the heart or the head - and that she knows how to do those shots is a given.

But that's it, right there. Mary is a trained assassin and she is standing right in front of Sherlock. So she definitely does have other options apart from shooting him. We have been over this before in various other threads, and I still believe that it would have been possible for her to incapacitate Sherlock without firing a single shot. I think it is a given that she knows how to accomplish this.
 


___________________________________________________
"Am I the current King of England?

"I see no shame in having an unhealthy obsession with something." - David Tennant
"We did observe." - David Tennant in "Richard II"

 
 

February 27, 2014 11:10 pm  #22


Re: An interesting NEW perspective

Swanpride wrote:

This is still a TV show, not a documentary about gun shot wounds, and the meta discussed it as such. It mostly illustrates that if we assume that the writers wanted the "surgery" situation and then asked a medical expert what place of the body would be a believable target, this would be the point they would come up with, for various reasons. That this can go wrong, really badly, in real life should be pretty clear - in fact the meta theorizes that it DID go wrong right there in the show, because Mary hit something she didn't intend to hit.

I say it one last time (because we are going in circles here): Mary is a trained assassin who is standing directly in front of Sherlock. She has the pick to shot him either in the heart or the head - and that she knows how to do those shots is a given. Even a hunter knows how to do an ideal kill shot, because the flesh tastes better if the prey has no time to feel fear. The theory that she was trying to derail John is not holding up, because in this case she could simply shot Sherlock in the abdomen, which would kill him for sure, too, just slower. But the spot she did pick was the liver. The one spot which has a very high survival rate. So why should she shot Sherlock in this place if she didn't want to give him a chance for survival?

I really don't see any reason why Sherlock should lie for her. Why should he encourage John to forgive and life with someone who might try to murder him? He even goes so far to tell John that he should trust Mary while breaking down...those could be his last words, but he insists on saying them.

I am trying hard to be polite about the anonymous medic who wrote the meta you cite, but even a non acute trauma specialist knows that cherry picking one piece of research on gunshot liver injuries when Pubmed is knee deep in reports of much larger studies with much higher mortality rates goes beyond the bounds of acceptable scribbling and comes exceedingly close to deliberate misrepresentation.

In other words, anyone idiotic enough to rely on a small case series whilst ignoring much larger ones is allowing sentiment to affect their judgement. It is unsurprising that other people are pointing out it is nonsense; the reason for this is that it is nonsense.

It is equally nonsensical to suggest that someone bleeding out, as Sherlock was, is in any fit state to judge who should be trusted and who should not. In order for the brain to function it needs oxygen; someone bleeding out is highly deficient in oxygen, and thus not exactly at their intellectual peak...

 

 

February 27, 2014 11:15 pm  #23


Re: An interesting NEW perspective

clareiow wrote:

Crikey I didn't think this would cause THIS much debate! As I know it has been trawled over so many times before - the reason I posted it wasn't necessarily because of the anatomical theorising of the post.

What threw me completely was, from the screengrabs, that it MIGHT not have been Mary who called the ambulance. It COULD have been CAM. He's leaning down in the background to where the phone was that Mary, according to Sherlock, called 999.

For me, through all of the anatomical diagrams and medical jargon, that part was the most interesting. I had not thought of it at all. We see, but we do not observe?

Quite so. And I would be willing to wager folding money that a 999 call from a billionaire probably would generate a more rapid response than an anonymous call which, as far as they know, could be a hoax.
 

 

February 28, 2014 12:25 am  #24


Re: An interesting NEW perspective

Actually,  I have been watching Due South, lured by one of our fellow posters who does not even like the show herself, who put me onto the fanfic, and when 'I'd run out of fanfic, I went to find the episodes,  and the rest is history.

We really do have some amazingly kind and helpful people on this forum; I thank you kindly 

 

February 28, 2014 6:55 am  #25


Re: An interesting NEW perspective

Willow wrote:

I am trying hard to be polite about the anonymous medic who wrote the meta you cite, but even a non acute trauma specialist knows that cherry picking one piece of research on gunshot liver injuries when Pubmed is knee deep in reports of much larger studies with much higher mortality rates goes beyond the bounds of acceptable scribbling and comes exceedingly close to deliberate misrepresentation.

In other words, anyone idiotic enough to rely on a small case series whilst ignoring much larger ones is allowing sentiment to affect their judgement. It is unsurprising that other people are pointing out it is nonsense; the reason for this is that it is nonsense.

I tried to search litrature on this subject systematically and so far I didn't have much sucess. Combined search of two detabases uncovered a grand total of 3 articles, all being case series. The article quoted by the author is the largest case series I managed to find so far (153 people over 10 years is not bad). For obvious reasons there aren't going to be any randomised control trials so the best we can hope in terms of evidence is case series and maybe a cohort study.

It seems that you had much more like with Pubmed. Could you point me towards any of the larger studies you found?

 

February 28, 2014 9:12 am  #26


Re: An interesting NEW perspective

belis wrote:

Willow wrote:

I am trying hard to be polite about the anonymous medic who wrote the meta you cite, but even a non acute trauma specialist knows that cherry picking one piece of research on gunshot liver injuries when Pubmed is knee deep in reports of much larger studies with much higher mortality rates goes beyond the bounds of acceptable scribbling and comes exceedingly close to deliberate misrepresentation.

In other words, anyone idiotic enough to rely on a small case series whilst ignoring much larger ones is allowing sentiment to affect their judgement. It is unsurprising that other people are pointing out it is nonsense; the reason for this is that it is nonsense.

I tried to search litrature on this subject systematically and so far I didn't have much sucess. Combined search of two detabases uncovered a grand total of 3 articles, all being case series. The article quoted by the author is the largest case series I managed to find so far (153 people over 10 years is not bad). For obvious reasons there aren't going to be any randomised control trials so the best we can hope in terms of evidence is case series and maybe a cohort study.

It seems that you had much more like with Pubmed. Could you point me towards any of the larger studies you found?

Well, the one which obviously appeals, not least because of the name which seems distinctly Sherlockian:

'Gunshot injuries of the liver: the Baragwanath experience.
Degiannis E1, Levy RD, Velmahos GC, Mokoena T, Daponte A, Saadia R.
Author information

Abstract
BACKGROUND:
This study comprised 304 patients with gunshot injuries of the liver, many of which from high-velocity firearms. The purpose of this study is to evaluate our management policy in gunshot injuries of the liver in light of our recent wider experience.'

This is double the number of cases in the study relied on by the meta writer; it really does not make any sense to choose the small case series when you have one twice as large with different results.

There is also the blindingly obvious fact that case series can only cover the number of people who survived sufficiently long to reach the hospital and be treated. I would suggest that no one in their right minds assumes that all patients shot in the liver survive until they reach hospitals    though obviously I do not wish to trespass on your territory

 

Last edited by Willow (February 28, 2014 9:14 am)

 

February 28, 2014 10:09 am  #27


Re: An interesting NEW perspective

Whats really funny here is Marys reactions as Sherlock gives his..she saved me..mixed messages bleh @ John.
Marys wide surprised eyes..her dropped jaw..her gobsmacked face..the moments of confusion..shaking her head in disbelief as she agrees with Sherlock in a errr yeah what he said way...
It's obviously the first time she has ever considered..heard anything like this excuse.
If you have ever caught two children doing something wrong..and one makes up a crazy it wasn't us excuse while the other nods amazed along....agreeing and hoping to get off.
Well thats how that scene goes.

Last edited by lil (February 28, 2014 10:10 am)

 

February 28, 2014 10:33 am  #28


Re: An interesting NEW perspective

lil, you're right, agreeing is what she mostly does in this whole scene. She doesn't really volunteer any information herself, it's Sherlock who gives information and does most of the talking. And for quite a long while Mary is just standing there, watching and saying nothing. And eventually she is agreeing with Sherlock that yes, she is the way she is because John chose her. Maaahhh! Good for her that Sherlock gave such a convenient explanation... 


___________________________________________________
"Am I the current King of England?

"I see no shame in having an unhealthy obsession with something." - David Tennant
"We did observe." - David Tennant in "Richard II"

 
 

February 28, 2014 11:02 am  #29


Re: An interesting NEW perspective

Swanpride wrote:

It makes sense to use the smaller study because the results of the bigger study are not very telling for what we want to know. So, I'm not an expert and reading specific jargon in another language is always difficult, but if I read this correctly it says that the patients with Grade I and II injuries survived without any problems, as well as most of the ones with Grade III,  and then gives rates for dying during and after the operation for the grades III to V - but it doesn't say how many of the patience had a grade I and II injury and how many had an injury of the higher grades. In short, it doesn't give us (at least not in the summary) a simple number for the survival rate of liver shots, because this is apparently not the point of the study. It seems to be mostly a recommendation concerning the best treatment of the wounds. (hence the need to compare in which cases a sepsis was more likely) While the other study is specifically about the mortality rate for gunshot wounds in the liver. (note that in this study 11 of the patients had shotgun wounds).

 
No, it does not make sense to use a small study when there is one twice as large freely available with specific reference to high velocity firearms which is what Mary was using. She did not use a shotgun.

Scientific papers like these are written in order to provide information about the best ways of treating wounds to reduce mortality and morbidity. Strange as it may seem to you, doctors don't write papers to provide handy little numbers for use by obsessed Sherlockians, and someone who cites a small case series when there is a much larger one available either hasn't bothered to do the research or is cherry picking.

And you still haven't even acknowledged that by definition no paper relating to the hospital treatment of people who have been shot in the liver can give an estimate of how many people die as a result of being shot in the liver because only the ones who survive long enough to reach a hospital can be included in a case series...

 

February 28, 2014 11:04 am  #30


Re: An interesting NEW perspective

lil wrote:

Whats really funny here is Marys reactions as Sherlock gives his..she saved me..mixed messages bleh @ John.
Marys wide surprised eyes..her dropped jaw..her gobsmacked face..the moments of confusion..shaking her head in disbelief as she agrees with Sherlock in a errr yeah what he said way...
It's obviously the first time she has ever considered..heard anything like this excuse.
If you have ever caught two children doing something wrong..and one makes up a crazy it wasn't us excuse while the other nods amazed along....agreeing and hoping to get off.
Well thats how that scene goes.

Yep; you've got it. 
 

 

February 28, 2014 11:17 am  #31


Re: An interesting NEW perspective

Willow wrote:

lil wrote:

Whats really funny here is Marys reactions as Sherlock gives his..she saved me..mixed messages bleh @ John.
Marys wide surprised eyes..her dropped jaw..her gobsmacked face..the moments of confusion..shaking her head in disbelief as she agrees with Sherlock in a errr yeah what he said way...
It's obviously the first time she has ever considered..heard anything like this excuse.
If you have ever caught two children doing something wrong..and one makes up a crazy it wasn't us excuse while the other nods amazed along....agreeing and hoping to get off.
Well thats how that scene goes.

Yep; you've got it. 
 

 
Dark comedy in the victorian gothic 221b at its very best....so very Moftiss.
So very funny in recollection.

 

February 28, 2014 11:31 am  #32


Re: An interesting NEW perspective

Willow wrote:

lil wrote:

Whats really funny here is Marys reactions as Sherlock gives his..she saved me..mixed messages bleh @ John.
Marys wide surprised eyes..her dropped jaw..her gobsmacked face..the moments of confusion..shaking her head in disbelief as she agrees with Sherlock in a errr yeah what he said way...
It's obviously the first time she has ever considered..heard anything like this excuse.
If you have ever caught two children doing something wrong..and one makes up a crazy it wasn't us excuse while the other nods amazed along....agreeing and hoping to get off.
Well thats how that scene goes.

Yep; you've got it.
 

A little bit like the smoking scene at Christmas? Only that Sherlock blamed Mycroft instead of defending Mary. But nevertheless a lie?

 

February 28, 2014 11:44 am  #33


Re: An interesting NEW perspective

Willow wrote:

lil wrote:

Whats really funny here is Marys reactions as Sherlock gives his..she saved me..mixed messages bleh @ John.
Marys wide surprised eyes..her dropped jaw..her gobsmacked face..the moments of confusion..shaking her head in disbelief as she agrees with Sherlock in a errr yeah what he said way...
It's obviously the first time she has ever considered..heard anything like this excuse.
If you have ever caught two children doing something wrong..and one makes up a crazy it wasn't us excuse while the other nods amazed along....agreeing and hoping to get off.
Well thats how that scene goes.

Yep; you've got it.
 

Very well observed. 
 


------------------------------
"To fake the death of one sibling may be regarded as a misfortune; to fake the death of both looks like carelessness." Oscar Wilde about Mycroft Holmes

"It is what it is says love." (Erich Fried)

“Enjoy the journey of life and not just the endgame. I’m also a great believer in treating others as you would like to be treated.” (Benedict Cumberbatch)



 
 

February 28, 2014 3:00 pm  #34


Re: An interesting NEW perspective

Swanpride wrote:

@Willow So perhaps you can tell me how many of the patients died according to the larger study? Perhaps I read it wrong, but since every per cent number we get refers specifically to a higher level of injury, and we don't know how many of the victims had this level of injury (for all we know, they are talking only about 20 patients there while everyone else was level I or II), we could be talking about one single patient which actually died.
Never mind that the large study confirmed at least one thing: The largest problem with liver injuries is the bleeding. This concurs with the smaller study and with what was shown during the show.

And since Sherlock got hospital treatment and Mary made sure that he got it, I really don't see how people who don't get any figure into this.

You haven't bothered to do even the most basic research on the hospital in question; if you had then you would know that it is the largest acute hospital in the world, with almost 3000 beds, and that 50% of the patients had stab or gunshot wounds.

In other words, they know their gunshot wounds better than anywhere other than a war zone, and indeed, they invite would be trauma surgeons to do their electives there, on the grounds that they will see vast numbers of cases which could only be matched in a war zone.

You don't seem to be interested in doing any research, and you don't seem interested in anything other than trying to claim that Mary was doing 'surgery' saving Sherlock's life.

We don't know that Mary ensured that Sherlock got hospital treatment; as the author of the more accurate meta notes the screenshots show CAM using what looks like a phone. As I have noted, a billionaire requesting an ambulance would be likely to get one faster than an anonymous caller; 999 gets plenty of hoax calls, which is why all messages are recorded, and from time to time legal action is taken against people making those calls.

And no one in London imagines that you could rely on an ambulance turning up in precisely 8 minutes; there's this thing called traffic which plays havoc with average numbers. Mary certainly attempted at the end to prevent CAM taking effective action to save Sherlock's life by pistol whipping him; we have things called air ambulances which are used where possible for really urgent cases. The Royal London, which is the major trauma centre, has a helipad, and CAM's headquarters has a helipad; it's not difficult to connect the dots to see how CAM could have got him to hospital really quickly had he not been pistol whipped by Mary.

If you really are unable to grasp that it is impossible to estimate mortality rates by looking only at people who survive long enough to get to a hospital, then I can't think of any better way of explaining it to you. It is a very simple and straightforward point...
 

 

February 28, 2014 3:15 pm  #35


Re: An interesting NEW perspective

Mod's note: 
A lively discussion is fine but please refrain from getting personal. 

Last edited by SusiGo (February 28, 2014 3:15 pm)


------------------------------
"To fake the death of one sibling may be regarded as a misfortune; to fake the death of both looks like carelessness." Oscar Wilde about Mycroft Holmes

"It is what it is says love." (Erich Fried)

“Enjoy the journey of life and not just the endgame. I’m also a great believer in treating others as you would like to be treated.” (Benedict Cumberbatch)



 
 

February 28, 2014 3:30 pm  #36


Re: An interesting NEW perspective

My apologies; I am in the process of trying to strip Office off my computer and reinstall it so that it doesn't immediately crash whenever I try to open Word. I really should know better than to try grappling with Microsoft and posting at the same time...

 

February 28, 2014 3:51 pm  #37


Re: An interesting NEW perspective

My sympathies.  I switched to Mac five years ago and never looked back. 


------------------------------
"To fake the death of one sibling may be regarded as a misfortune; to fake the death of both looks like carelessness." Oscar Wilde about Mycroft Holmes

"It is what it is says love." (Erich Fried)

“Enjoy the journey of life and not just the endgame. I’m also a great believer in treating others as you would like to be treated.” (Benedict Cumberbatch)



 
 

February 28, 2014 6:07 pm  #38


Re: An interesting NEW perspective

Swanpride wrote:

Yeah, but would be believe Mary anything she says? It would just sound like a feeble excuse. Sherlock deducing it makes it way more official than the world of a lying ex-assassin.

Makes sense, because (obviously) Mary is a lying ex ?, really?  Assassin!

 

February 28, 2014 6:11 pm  #39


Re: An interesting NEW perspective

Swanpride wrote:

I honestly don't get why you are so aggressive (again). I just asked a simple question: Is it possible to tell from the data of the larger study, how many of the gunshot victims died? As far as I can tell it isn't, but perhaps I read it wrong. In this case I would be interested in the number and how you are able to tell it based on the data available. And knowing how many victims the hospital in question is caring for in general wouldn't help, because we are searching for empiric data specifically for the mortality rate of gunshots in the liver.

Huh. I thought the biggest problem for Sherlock was getting clipped in the Inferior vena cava. 70-90% die from that. 

From the meta I posted: 

Penetrating trauma accounts for 90–95% of abdominal vascular injuries, with a high mortality due to the nature of these injuries as well as associated injuries to other intra-abdominal organs. It is important to consider intra-abdominal injury with all penetrating injuries from the nipples to the upper thighs.

The retro-hepatic IVC should be approached with extreme caution. If haemorrhage can be controlled with packing this should be the method of treatment. Various strategies to repair these injuries have been described but the prognosis is still dismal, with a reported mortality of 70–90%. 
Mortality means death. Death in 70-90% of cases. D E A D. 

Let's tally up the score then, shall we?

I am going to review all of Sherlock's injuries (from the outside in) by dividing things up into lists (I LOVE lists!!) and seeing what pathology each injury would result in.

 Definite Injuries:

Right Pectoralis Major muscle
Right Rectus Abdominis muscle: Rectus sheath haematoma
5th CC/Rib: Rib Fracture/ Haemothorax/ Tension Pneumothorax/ Liver Injury
Internal Thoracic artery and vein: Haemothorax
Middle lobe of the right lung: Pneumothorax
Diaphragm
Liver: SHOCK/ Liver Injury
IVC: SHOCK/ Vascular Injury
 I have no doubt about these whatsoever.

Possible Injuries:

5th intercostal neurovascular bundle: Paralysis of intercostal muscles and sensory loss
Right parasternal lymphatic chain: Chylothorax
Right atrium of the heart: Cardiac Tamponade
Right phrenic nerve: Unilateral diaphragmatic paralysis
The reason I have the list with possible injuries is to prove a point.

Had Sherlock been in a different phase of respiration (remember ribs move with respiration), the course of the bullet would have been completely different, and Mary would have broken his heart. Quite literally.

++
Hope this helps clarify! :-)

Last edited by RavenMorganLeigh (February 28, 2014 6:19 pm)

 

February 28, 2014 6:42 pm  #40


Re: An interesting NEW perspective

Willow wrote:

'Gunshot injuries of the liver: the Baragwanath experience.
Degiannis E1, Levy RD, Velmahos GC, Mokoena T, Daponte A, Saadia R.
Author information

Abstract
BACKGROUND:
This study comprised 304 patients with gunshot injuries of the liver, many of which from high-velocity firearms. The purpose of this study is to evaluate our management policy in gunshot injuries of the liver in light of our recent wider experience.'

This is double the number of cases in the study relied on by the meta writer; it really does not make any sense to choose the small case series when you have one twice as large with different results.

There is also the blindingly obvious fact that case series can only cover the number of people who survived sufficiently long to reach the hospital and be treated. I would suggest that no one in their right minds assumes that all patients shot in the liver survive until they reach hospitals though obviously I do not wish to trespass on your territory  

I can’t argue with the fact that neither of the studies takes into account people who expire before reaching the hospital. It’s an important limitation, which illustrates the challenges of trying to practice evidence based medicine. It’s not that easy to find studies that apply perfectly to the population we are interested in.

There is however an important caveat. Wellingtongoose uses the 8% statistic to compare the mortality rates between liver and thoracic injuries, not to talk about mortality in absolute terms.

‘The mortality rate for the entire group attributed to liver injuries was 8% (12). Thus the chances of surviving a shot to the liver are 92 percent. Compare this to a thoracic gunshot wound which has a mortality rate of around 20-30%.’
 Consequently we can forget about people who die outside of the hospital as the same confounder is going to apply to both groups of interest (liver and thoracic injury).
 
Why did he choose to reference this paper and not the larger study? I suspect the main reason is that to obtain the mortality rate from Baragwanath study you need to do some leg work. The abstract doesn’t provide that information. To read the full article you either need to pay or be a subscriber. The

When you get hold of the full article some calculations are required.

Out of the total sample of 304 patients 19 died directly from their liver injuries giving a mortality rate of 6.2 %. That’s lower than figure quoted by Wellingtongoose. Majority of patients (241) ended up with grade I-III injuries and most of them didn’t need operating on. Only 4 of those patients died as a direct result of the trauma to the liver.

So in fact the larger study does confirm that liver is not such a bad place to be shot at in a grand scale of things.
 

Last edited by belis (February 28, 2014 6:44 pm)

 

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